Hewlett Packard Enterprise (HPE) has announced an expanded NVIDIA AI Computing by HPE portfolio to accelerate artificial intelligence (AI) adoption across governments, regulated industries, and enterprises. The portfolio is designed to make AI easier to deploy and scale securely through turnkey AI factory solutions, unified data strategies, and updated server platforms featuring NVIDIA’s latest infrastructure and software.
With AI rapidly transforming multiple sectors, many organisations continue to face fragmented goals and data challenges. According to the 2025 Architecting an AI Advantage report, nearly 60 percent of organisations lack cohesive AI strategies and comprehensive data management. HPE and NVIDIA aim to close this gap with a complete suite of solutions for AI factories, enabling enterprises and sovereign cloud builders to develop a unified AI infrastructure approach.
Fidelma Russo, executive vice president and chief technology officer of HPE, said, “To accelerate widespread AI adoption in enterprises, technology must directly address the core challenges that organisations face around complex deployments and fragmented, highly sensitive data. Together with NVIDIA, we offer a different approach with full-stack, private AI factories that simplify operations and help enterprises and governments scale quickly while staying compliant.”
Justin Boitano, vice president of Enterprise Software at NVIDIA, added, “AI factories are the new infrastructure of the intelligence era — built to generate tokens of intelligence at massive scale. NVIDIA and HPE are building these full-stack systems — integrating NVIDIA Blackwell, NVIDIA networking software, and AI Data Platform reference designs — to power agentic AI, unlock automation, and accelerate digital transformation for every industry.”
The second generation of HPE Private Cloud AI, developed with NVIDIA, is now available in a compact form to accelerate AI deployment across enterprises. The turnkey AI factory includes several new enhancements, such as the HPE ProLiant Compute DL380a Gen12 servers and NVIDIA RTX PRO 6000 Blackwell Server Edition GPUs. These deliver up to three times better price-to-performance for enterprise AI workloads and have achieved seven top rankings in MLPerf Inference v5.1 benchmarks.
For government use, the AI factory supports the new NVIDIA AI Factory for Government, a full-stack reference design that meets high-assurance compliance standards and enables management of multiple AI workloads across on-premises and hybrid environments. A new air-gapped management capability supports secure, network-isolated deployments, essential for sovereign and regulated organisations.
HPE Services is also introducing an offering that uses HPE Private Cloud AI and NVIDIA NeMo to create digital avatar assistants for smart cities and sectors such as retail, healthcare, manufacturing, finance, and education. Meanwhile, a new system adoption accelerator service provides post-installation testing and training for data science teams to speed up AI implementation.
The Town of Vail serves as a lighthouse customer for HPE’s new Agentic Smart City Solution, which uses agentic AI systems to scale from pilot projects to full citywide smart infrastructure. Partnering with SHI, NVIDIA, and HPE Unleash AI validated partners, the initiative supports accessibility compliance, permitting, and wildfire detection.
Enhancing data pipelines and governance
HPE also introduced new capabilities for its unified data layer to improve governance and AI data management in air-gapped environments. Using HPE Data Fabric Software and HPE Alletra Storage MP X10000, the system combines a global namespace with advanced data intelligence to support AI pipelines. Integrated with NVIDIA’s AI Data Platform, it enables efficient feeding of data to applications and models.
The X10000 can now be managed in isolated environments, offering cloud-like management while maintaining network restrictions. It also supports NVIDIA’s S3oRDMA solution for faster data transfer between GPUs and storage. In addition, HPE Data Fabric now includes agentic AI-powered governance through the Model Context Protocol, which enhances compliance, data federation, and governance across structured and unstructured data.
Expanding AI infrastructure at scale
HPE has introduced new offerings within the NVIDIA AI Computing by HPE portfolio for scalable AI deployments. The HPE ProLiant Compute XD685 supports up to eight NVIDIA Blackwell Ultra GPUs and is designed for large AI clusters. Meanwhile, the NVIDIA GB300 NVL72 by HPE, capable of training AI models with more than one trillion parameters, will be available for order with shipments expected in December 2025.
The HPE ProLiant Compute DL380 Gen12 Server Premier Solution for Azure Local brings select Azure services and AI capabilities directly to data centres, while supporting NVIDIA RTX PRO 6000 GPUs for various AI and virtual workloads.
HPE has also expanded NVIDIA GPU options across eight ProLiant platforms, enabling sectors such as education, finance, and healthcare to deploy scalable, high-performance AI infrastructure. Upcoming ProLiant and Cray server models will include support for NVIDIA Rubin CPXs, Vera Rubin CPX platforms, and the BlueField-4 DPU, which provides up to 800 Gb/s throughput for gigascale AI factories.
